Abnormal pseudocholinesterase

The Evaluation of Serum Pseudocholinesterase

DESPITE numerous tests used in the diagnosis of liver disease, in manv cases it is still difficult to decide whether there is liver damage, and if so, how much. This study was done to evaluate serum pseudocholinesterase estimation as a routine test of liver function, and to conmpare it with certain commonly used tests, viz., serum bilirubin, zinc sulphate flocculation test, thymol turbidity tes...

Pseudocholinesterase activity in thyroid disease.

The present evidence indicates that serum pseudocholinesterase activity is increased to about 20% above the normal level in thyrotoxicosis and decreased by about 30% in myxoedema. Treatment restores the esterase level to the average mean activity of random normal as the patient becomes euthyroid. There is no evidence in the present investigation that any of the pseudocholinesterase variants mod...

Sertraline-induced pseudocholinesterase enzyme deficiency

A 47-year-old Turkish male was scheduled for laparoscopic cholecystectomy under general anesthesia. The patient had 2 operations 28 and 19 years ago under general anesthesia. It was learned that the patient was administered succinylcholine during both of these previous operations and that he did not have a history of prolonged recovery or postoperative apnea. The patient had been using sertrali...

Pseudocholinesterase activity and atracurium v. suxamethonium block.

Serum pseudocholinesterase activity in pregnant women was assayed spectrophotometrically using either propionylthiocholine or suxamethonium as substrate. All patients had a normal phenotype as indicated by normal dibucaine and fluoride numbers. However, the mean cholinesterase activity was lower than in the general population. There was a negative correlation between cholinesterase activity and...

The implications of pseudocholinesterase in anesthesia.